A Cure for AIDS

Mad4it · Nov 14, 2008

Originally posted by Ferox
As has been stated, bone marrow transplants are simply too risky for this to be considered as a viable cure to HIV. What could be interesting is carrying out gene therapy research on people who are resistant to HIV (such as the donor).

HIV has been considered as a manageable condition (like diabetes) in the developed world for a while now. Through anti retroviral treatment, the amount of the virus in the blood can be lowered to undetectable levels, making the chances of transmission virtually zero. Where the problem is is Africa. Drugs are simply too expensive for your average African infected with HIV to afford, and added to this, a different strain is prevalent in most of Africa (HIV-2), which although less infectious than the more common strain at first, is much more viral in later stages of the disease. This is why HIV in Africa is considered a ticking time bomb. And there are also subtle differences as to how you treat the different strains, and it is difficult to measure the viral loads (how much of the virus is in the body) of people with HIV-2, so who knows if this 'cure' (from a white European resistant to HIV) will apply to African's? In the meantime drug companies need to allow cheap generic versions of their drugs to be made available to Africa as the HIV prevalence rates are really scary.
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I think i'll take the diabete's thanks!!

stu · Nov 14, 2008

a drug cure to aids is gonna be really hard to get out, the pharmaceutical companies make way too much money treating aids to consider the one off payment curing option imo

Oasis · Nov 14, 2008

That must be shit like. Having AIDS and leukaemia (at the same time)

Willa · Nov 14, 2008

Originally posted by Oasis
That must be shit like. Having AIDS and leukaemia (at the same time)
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[yt]-crL4yzMhTk[/yt]

Oasis · Nov 14, 2008

Originally posted by Willa
[yt]-crL4yzMhTk[/yt]
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I dont know who's worse. the bloke that took the time out to create that pile of shite or you for posting it.

Hebburnite · Nov 14, 2008

Originally posted by andy_rocks
This only works because you have to basically wipe out the entire host immune system first before you squirt the new one in. Then the new immune system always attacks the new body to some extent because they don't match properly. This is tolerable if you have cancer and were going to die anyway, but not worthwhile in HIV, because in the developed world you can suppress it so well with modern drugs.

The challenge is making the drugs cheap enough to use in Africa before those humans in Africa without the mutation are naturally selected out.
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There are cases of African prostitutes whose body has rid itself of AIDs - they are the people they should be looking for towards a vaccine!

Willa · Nov 14, 2008

Originally posted by Oasis
I dont know who's worse. the bloke that took the time out to create that pile of shite or you for posting it.
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either way, the song is bang on.

Hebburnite · Nov 14, 2008

Originally posted by MistaK
the fact that it cost's 25 grand.

wait there....i'll say that again.

25 grand. and even then there isnt the slightest clue that it will work, and ya dont even get ya cash back either if it doesnt

it hasnt actually done that much good to start off with, it basically just extends life for 3 month. if i got struck with terminal or had avastin as a last straw i'd take that 25 grand and spend it on killing myself faster - and that seriously is no exaggeration.

the pharmacutical companies must just be cashing in on this? at least thats the way it seems.

is the dose constant or something?!
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If this seemingly shocks you - you should look into the price of antibiotics etc and the sheer amount the NHS dispenses. A ratio of patients against mass makes 25k look fuck all

MistaK · Nov 14, 2008

Originally posted by Allie
what are you basing your "25 grand" on? i explained earlier wy drugs are so expensive, especially when they're new. you can pick up generic versions of paracetamol, ibuprofen and other NSAIDs for less than 50p, but that's because they've been about for years and the patents have run out. whoever developed avastin (i ashamedly don't know this, but it's more than likely gsk) will have but an almighty amount of money into it since the early-to-mid nineties, and now it's commercially available, will need to recoup some of those costs.

for the record, it does work, it's only GIT and breast cancers which it doesn't really affect. what else, other than to "basically just prolong life for 3 months" would you expect it to do? given that cancer is an uncurable disease...
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it's roche who produces avastin. and 25K is the price of it, i thought with your depth of knowledge in the field you would of known.

and i'm just saying that, bearing in mind that all it's doing is prolonging life, is sticking a price tag on what precious time there IS left. i really dont see the point in it. in that extra time i'd be guilty that i was playing false gods.

Allie · Nov 14, 2008

Originally posted by MistaK
it's roche who produces avastin. and 25K is the price of it, i thought with your depth of knowledge in the field you would of known.

and i'm just saying that, bearing in mind that all it's doing is prolonging life, is sticking a price tag on what precious time there IS left. i really dont see the point in it. in that extra time i'd be guilty that i was playing false gods.
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i'm guessing you mean 25k per course of treatment? is treatment indefinite? i know it's in fortnightly doses, but is it 25k irrespective of whether you receive one or twenty?

roche aren't somebody i know a lot about to be honest, but given that they're not one of the three large producers (gsk, astrazeneca, pfizer), that's even more reason why they need to recouperate costs.

i'm not trying to be high and mighty or get on any form of high horse here, just trying to give a pharmacological point of view to balance out all the conspiracy theorists.

Oasis · Nov 14, 2008

Originally posted by Willa
either way, the song is bang on.
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You chump!

Willa · Nov 14, 2008

Originally posted by Oasis
You chump!
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typical shit mackem crack, well in

MistaK · Nov 14, 2008

Originally posted by Oasis
You chimp!
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indeed!

Oasis · Nov 14, 2008

Originally posted by Willa
typical shit mackem crack, well in
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keep em coming

Oasis · Nov 14, 2008

Originally posted by MistaK
indeed!

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That picture is bang on!

MistaK · Nov 14, 2008

Originally posted by Allie
i'm not trying to be high and mighty or get on any form of high horse here, just trying to give a pharmacological point of view to balance out all the conspiracy theorists.
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yeah, i know your providing the argument from the Pharm Coop's, and dont hold grudge (you infadel!!)

however i just think it's a proper middle class drug. a vast majority can't afford it. and for little outcome. apparently it will never cure (obv.) but there isnt much chance of it prolonging life past 3 month.

all i'm saying - if i was paying that much loot for that kind of gear, i'd be pretty gutted.

they obv bash it too much.

MistaK · Nov 14, 2008

Originally posted by Oasis
That picture is bang on!
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sorry, couldent help myself. and tbf, i dont even like football.

but it seems almost mandatory to stand in your corner regardless

but it's rich coming from a person from a half-breed town like south shields.

Oasis · Nov 14, 2008

Tbf I don't know what AIDs or leukaemia has got to do with Football. You're better off asking Willa.

Congay · Nov 14, 2008

Zombie bone suckers

Did you know ppl who are resistant to HIV are also resistant to The Black Death?

Lee · Nov 15, 2008

its about time the world opened up to the possibilities of stem cells, a blank cell hat can replicate whatever instructions it is given is surely one of the most beneficial technological advances of our time, if god didnt want us to use stem cells he wouldnt have invented the brain

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